What is Panacos Graft Procedure?
Panacos Graft is a surgical approach to plantars warts. In the l970’s it was discovered that the etiology of many clinical types of warts was the human papilloma virus (HPV). Clinical and scientific observation further revealed a higher incidence of warts associated with immune system deficiencies and abnormalities. Immunology studies have uncovered incidence of lymphocytes, mononuclear phagocytes and infiltrating T lymphocytes in cellular infiltrates taken from regressing plane warts. Both lymphocytes and some mononuclear phagocytes were found adjacent to keratinocytes near the epidermis. This suggests that cell-mediated immunity plays an active role in combating verruca infections.
Treatment of Warts with Panacos Graft
The podiatrists at Foot Centers of NC are highly skilled in the treatment of warts and the Panacos Graft is a commonly used procedure that treats patients with chronic outbreaks of this virus. It is performed in our office and requires very little recovery time.
Panacos Graft procedure
The Panacos Graft procedure, discovered by Dr. Nikos Panacos and others in the l970s, involves cutting out verrucoid tissue and implanting it underneath the skin of a predetermined recipient site. It is believed that this graft triggers an autoimmune response of the host to the verrucae that eventually will cause the HPV to regress.
• To lessen pain, a local anesthetic is used on both the donor and recipient site before the procedure begins.
• Once the areas are numbed, the wart or warts are removed and tissue from the donor wart is implanted underneath the skin at another site; usually in a non-weight bearing area of the opposite foot.
• The tiny incisions are then closed using sutures.
• Sterile compression dressings are applied to both donor and recipient sites.
• The patient is then seen one week following the procedure.
• From three weeks before the procedure until three weeks afterward, it is imperative that no antibiotics be used because of the risk of interfering with the autoimmune response.
The Panacos Graft technique has a very high success rate and can be performed on patients of all ages. It has proven to be very beneficial in helping patients who had previously been burdened with debilitating plantar warts. To learn more about this procedure, consult your podiatrist at Foot Centers of NC.